Pregnancy Complicated by Chronic Pulmonary Aspergillosis

Chronic pulmonary aspergillosis (CPA) is primarily seen in individuals with pre-existing lung pathology like bronchiectasis, cystic fibrosis, chronic obstructive pulmonary disease, or subtle immune compromise. It is rare in pregnancy and poses significant diagnostic and therapeutic challenges. We report a rare case of CPA in a young pregnant woman who was initially diagnosed with bronchiectasis secondary to meningococcal septicaemia in early childhood. She had recurrent haemoptysis during both pregnancies. During her current pregnancy, she presented with worsening respiratory symptoms and was ultimately managed with bronchial artery embolisation. Surgical intervention was deferred until postpartum. A planned caesarean delivery was undertaken at 34 weeks and 2 days due to the risk of massive haemoptysis. Postpartum, she was initiated on antifungal therapy and subsequently underwent definitive treatment with right lower pulmonary lobectomy. This case underscores the importance of appropriate diagnosis and timely management of complex respiratory conditions during pregnancy, particularly the role of a multidisciplinary team.

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Publication Details

Journal
Cureus
Published
2025-10-18
DOI
https://doi.org/10.7759/cureus.94851
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
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article

Pregnancy Complicated by Chronic Pulmonary Aspergillosis

Hassaan Malik, Wan Faizal Wan Rahimi Shah
Cureus
Antifungal resistance and susceptibility
article

Pregnancy Complicated by Chronic Pulmonary Aspergillosis

Hassaan Malik, Wan Faizal Wan Rahimi Shah
article en

Abstract

Chronic pulmonary aspergillosis (CPA) is primarily seen in individuals with pre-existing lung pathology like bronchiectasis, cystic fibrosis, chronic obstructive pulmonary disease, or subtle immune compromise. It is rare in pregnancy and poses significant diagnostic and therapeutic challenges. We report a rare case of CPA in a young pregnant woman who was initially diagnosed with bronchiectasis secondary to meningococcal septicaemia in early childhood. She had recurrent haemoptysis during both pregnancies. During her current pregnancy, she presented with worsening respiratory symptoms and was ultimately managed with bronchial artery embolisation. Surgical intervention was deferred until postpartum. A planned caesarean delivery was undertaken at 34 weeks and 2 days due to the risk of massive haemoptysis. Postpartum, she was initiated on antifungal therapy and subsequently underwent definitive treatment with right lower pulmonary lobectomy. This case underscores the importance of appropriate diagnosis and timely management of complex respiratory conditions during pregnancy, particularly the role of a multidisciplinary team.

CureusVol. 17(10)
Dumfries and Galloway Royal Infirmary (GB)
Openalex Percentile: Top 65%
Antifungal resistance and susceptibility
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