Research progress on the role of oxidative stress in the pathogenesis of vascular dementia and its treatment
The central role of oxidative stress in VaD provides new targets for treatment, but a shift from single-target antioxidant therapy to multi-level intervention is required. Future research should focus on developing targeted antioxidant therapies, exploring combination treatment regimens, and validating biomarkers applicable for early detection and therapeutic efficacy assessment.
Authors
- Junwei Zhou (ORCID: https://orcid.org/0000-0002-6094-1203)
- Yutong Liu (ORCID: https://orcid.org/0000-0003-2236-6962)
- Xinyu Yang (ORCID: https://orcid.org/0009-0002-6706-9857)
- Wentao Yu (ORCID: https://orcid.org/0000-0002-4381-7059)
- Xi-Qi Xu
- Hongxiao Lv
Institutions
- Capital Medical University (CN)
- Hebei University of Chinese Medicine (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2025-10-18
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108475
- Citations
- 4
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.37