HPV profiles in Botswana: An analysis of healthy women, cervical intraepithelial neoplasia, and invasive cervical cancer
Compared to healthy women, HPV subtype representation is higher among women with CIN and CaCx. This suggests the presence of multiple HR HPV strains may impact transformation from pre-cancerous lesions to CaCx, highlighting the importance of CIN detection and primary prevention of HR HPV to decrease the incidence of CaCx in Botswana.
Authors
- Caroline Kernell (ORCID: https://orcid.org/0000-0002-3624-9882)
- Doreen Ramogola‐Masire (ORCID: https://orcid.org/0000-0001-9624-8366)
- Surbhi Grover (ORCID: https://orcid.org/0000-0001-7443-5937)
- Erle S. Robertson (ORCID: https://orcid.org/0000-0002-6088-2979)
- Le Gao (ORCID: https://orcid.org/0000-0003-2625-8774)
- Xiang Lin (ORCID: https://orcid.org/0000-0002-7634-5780)
- Emily MacDuffie (ORCID: https://orcid.org/0000-0001-8479-8512)
Institutions
- New Jersey Institute of Technology (US)
- University of Botswana (BW)
- University of Pennsylvania (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Gynecologic Oncology Reports
- Published
- 2025-10-18
- DOI
- https://doi.org/10.1016/j.gore.2025.101971
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00