Robot-assisted extended thymectomy in juvenile myasthenia gravis: first case performed in Ecuador

Myasthenia gravis (MG) is a chronic autoimmune disorder characterized by fatigable muscle weakness, typically caused by antibodies against acetylcholine receptors (AChR) or muscle-specific kinas. While it primarily affects adults, juvenile cases represent a significant minority and often pose greater therapeutic challenges. Extended thymectomy has proven beneficial in AChR-positive MG, reducing symptoms and immunosuppressive needs. Robotic-assisted thymectomy offers enhanced precision with lower morbidity. We report the first such procedure in Ecuador, performed on a 21-year-old woman with recurrent myasthenic crises. The surgery was uneventful, and follow-up showed marked clinical improvement without recurrence, highlighting the feasibility of advanced techniques in low-resource settings.

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Journal
Journal of Surgical Case Reports
Published
2025-09-30
DOI
https://doi.org/10.1093/jscr/rjaf759
Primary Topic
Myasthenia Gravis and Thymoma
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article
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article

Robot-assisted extended thymectomy in juvenile myasthenia gravis: first case performed in Ecuador

Luis Adrián Muñoz Andrade, Enrique Antonio Gagliardo Cadena, Luis Alberto Barrera Delgado, Janneth Alejandra Pérez Cedeño et al.
Journal of Surgical Case Reports
Myasthenia Gravis and Thymoma
article

Robot-assisted extended thymectomy in juvenile myasthenia gravis: first case performed in Ecuador

Luis Adrián Muñoz Andrade, Enrique Antonio Gagliardo Cadena, Luis Alberto Barrera Delgado, Janneth Alejandra Pérez Cedeño, Luis Aguaguiña Toainga
article en

Abstract

Myasthenia gravis (MG) is a chronic autoimmune disorder characterized by fatigable muscle weakness, typically caused by antibodies against acetylcholine receptors (AChR) or muscle-specific kinas. While it primarily affects adults, juvenile cases represent a significant minority and often pose greater therapeutic challenges. Extended thymectomy has proven beneficial in AChR-positive MG, reducing symptoms and immunosuppressive needs. Robotic-assisted thymectomy offers enhanced precision with lower morbidity. We report the first such procedure in Ecuador, performed on a 21-year-old woman with recurrent myasthenic crises. The surgery was uneventful, and follow-up showed marked clinical improvement without recurrence, highlighting the feasibility of advanced techniques in low-resource settings.

Journal of Surgical Case ReportsVol. 2025(10)
University of Guayaquil (EC), Sinai Hospital (US)
Openalex Percentile: Top 58%
Myasthenia Gravis and Thymoma
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Robot-assisted extended thymectomy in juvenile myasthenia gravis: first case performed in Ecuador — Luis Adrián Muñoz Andrade, Enrique Antonio Gagliardo Cadena, et al. · Journal of Surgical Case Reports (2025) | TGRS Research Map | TGRS