Prognostic impact of Geriatric 8 and comprehensive geriatric assessment in older patients with advanced pancreatic ductal adenocarcinoma
First-line chemotherapy provides particular clinical benefit to older adults with PDAC with higher G8 scores, though benefit was observed across the broader cohort. The G8 score was a strong independent prognostic tool for treatment response and survival.
Authors
- Linda Di Francesco
- Lisa Salvatore (ORCID: https://orcid.org/0000-0003-3864-0719)
- Chiara Iacomini (ORCID: https://orcid.org/0000-0001-7701-1929)
- Cinzia Bagalá
- Giampaolo Tortora (ORCID: https://orcid.org/0000-0002-1378-4962)
- Jacopo Lenkowicz (ORCID: https://orcid.org/0000-0002-8366-1474)
- Maria Bensi (ORCID: https://orcid.org/0000-0002-5647-0525)
- Nicoletta Di Giorgi
- G. Trovato (ORCID: https://orcid.org/0009-0004-9526-0725)
- Laura Chiofalo
- A. Cosmai
- Alexia Spring
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Agostino Gemelli University Polyclinic (IT)
- University of the Sacred Heart (JP)
Publication Details
- Journal
- Journal of Geriatric Oncology
- Published
- 2025-10-18
- DOI
- https://doi.org/10.1016/j.jgo.2025.102782
- Citations
- 2
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Fondazione Italiana per la ricerca sulle Malattie del Pancreas
- Ministero della Salute
- Associazione Italiana per la Ricerca sul Cancro
- Ministero dell'Università e della Ricerca