Compensated biological effective dose in extended radiotherapy course via a time-modified linear quadratic model for biological adaptive radiotherapy
We developed a workflow to generate clinically deliverable plans that compensate for the decrease in BED due to treatment interruptions using the mLQ model. This approach may facilitate rapid compensation planning in clinical radiotherapy settings.
Authors
- Nobuki Imano (ORCID: https://orcid.org/0000-0002-7668-1506)
- Ikuno Nishibuchi (ORCID: https://orcid.org/0000-0001-5873-4822)
- Yuji Murakami (ORCID: https://orcid.org/0000-0003-3596-3010)
- Akito S Koganezawa (ORCID: https://orcid.org/0000-0002-7823-5884)
- Takuya Wada (ORCID: https://orcid.org/0009-0002-9232-9550)
- Daisuke Kawahara (ORCID: https://orcid.org/0000-0002-3598-1027)
Institutions
- Hiroshima University (JP)
- Hiroshima University Hospital (JP)
- Teikyo University (JP)
Publication Details
- Journal
- Physica Medica
- Published
- 2025-10-18
- DOI
- https://doi.org/10.1016/j.ejmp.2025.105202
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00