Do the expressions of HLA-G and killer cell immunoglobulin-like receptors change in colorectal cancer?

In conclusion, this study highlights the increased expression of both HLA-G and KIR markers in CRC patients, suggesting their potential as prognostic and predictive markers. Our findings also suggest that HLA-G and KIR molecules could represent valuable therapeutic targets for future cancer immunotherapy strategies.

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Publication Details

Journal
TURKISH JOURNAL OF MEDICAL SCIENCES
Published
2025-10-14
DOI
https://doi.org/10.55730/1300-0144.6073
Primary Topic
Reproductive System and Pregnancy
Type
article
Field-Weighted Citation Impact
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article

Do the expressions of HLA-G and killer cell immunoglobulin-like receptors change in colorectal cancer?

Fatma Savran Oğuz, Elvir Dincer, Çiğdem Kekik Çınar, Fatma Kaya Dağıstanlı et al.
TURKISH JOURNAL OF MEDICAL SCIENCES
Reproductive System and Pregnancy
article

Do the expressions of HLA-G and killer cell immunoglobulin-like receptors change in colorectal cancer?

Fatma Savran Oğuz, Elvir Dincer, Çiğdem Kekik Çınar, Fatma Kaya Dağıstanlı, Demet Kıvanç, Kıvanç Derya Peker, Figen Abatay Sel, Şule Karataş, Damlanur Sakız, Hayriye Şentürk Çiftçi
article en

Abstract

In conclusion, this study highlights the increased expression of both HLA-G and KIR markers in CRC patients, suggesting their potential as prognostic and predictive markers. Our findings also suggest that HLA-G and KIR molecules could represent valuable therapeutic targets for future cancer immunotherapy strategies.

TURKISH JOURNAL OF MEDICAL SCIENCESVol. 55(5)
University of Health Science (KH), Istanbul University-Cerrahpaşa (TR), Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR), Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi (TR), Istanbul University (TR), University of Health Sciences Antigua (AG)
Openalex Percentile: Top 69%
Reproductive System and Pregnancy
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