Baseline neurofilament light chain and brain-derived neurotrophic factor levels predict development of aggressive multiple sclerosis
Baseline NFL and BDNF levels effectively predict the development of AMS emerging early in the course of MS. Combined use of these molecular markers with MRI results may enable early diagnosis and appropriate therapeutic intervention of AMS.
Authors
- Devran Süer (ORCID: https://orcid.org/0000-0003-4119-6380)
- A. Ersöz (ORCID: https://orcid.org/0000-0002-7588-3376)
- Tuğçe Kızılay (ORCID: https://orcid.org/0000-0002-1092-5336)
- Vuslat Yılmaz (ORCID: https://orcid.org/0000-0002-4809-2966)
- Erdem Tüzün (ORCID: https://orcid.org/0000-0002-4483-0394)
- Recai Türkoğlu (ORCID: https://orcid.org/0000-0001-9724-851X)
- Ramazan Yıldız (ORCID: https://orcid.org/0000-0002-8007-7854)
- Ece Akbayır (ORCID: https://orcid.org/0000-0002-8148-6940)
- Duygu Özkan Yaşargün (ORCID: https://orcid.org/0000-0003-3723-6335)
Institutions
- HUN-REN Institute of Experimental Medicine (HU)
- Haydarpaşa Numune Eğitim ve Araştırma Hastanesi (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Istanbul University (TR)
Publication Details
- Journal
- TURKISH JOURNAL OF MEDICAL SCIENCES
- Published
- 2025-10-14
- DOI
- https://doi.org/10.55730/1300-0144.6067
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00