Quantitative Analysis of DNA Double‐Strand Breaks in Genomic DNA Using Standard Curve Method
This standard curve-based method enables accurate, reproducible quantification of genome-wide DSBs in various organisms. It is simple, low-cost, and easily standardized, offering a promising tool for applications in genotoxicity testing, environmental exposure monitoring, and DNA damage research.
Authors
- Chenwei Li (ORCID: https://orcid.org/0000-0003-2199-2398)
- Hanying Dai
- Lihuang Guo (ORCID: https://orcid.org/0000-0002-0946-5643)
- Keqian Xu (ORCID: https://orcid.org/0000-0001-9104-2473)
- Jiancheng Li (ORCID: https://orcid.org/0000-0003-3686-9958)
- Yue Huang (ORCID: https://orcid.org/0000-0002-5715-9392)
Institutions
- Central South University (CN)
- Third Xiangya Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Shenzhen Pingle Orthopedic Hospital (CN)
Publication Details
- Journal
- Journal of Clinical Laboratory Analysis
- Published
- 2025-10-18
- DOI
- https://doi.org/10.1002/jcla.70123
- Primary Topic
- Carcinogens and Genotoxicity Assessment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hunan Agricultural University