Research on Anti-tumor Pharmacodynamics of Multi-functional Magnetic Lipid Polymer with Specific Targeted Transmission of siRNA and its Toxicity Evaluation
GLPS/siRNA demonstrates good stability, tumor targeting, imaging capability, and antitumor efficacy with favorable safety, positioning it as a promising theragnostic platform for HCC. This integrated system provides novel clinical tools for diagnosis and treatment, establishes a foundation for clinical translation, and enables simultaneous tumor imaging and gene therapy-offering innovative strategies for combined tumor theranostics.
Authors
- Guangyu Jin (ORCID: https://orcid.org/0000-0002-3246-3574)
- Jishan Quan
- Yaru Liu
- Jie Jin (ORCID: https://orcid.org/0000-0003-2440-7983)
- Chang Wang (ORCID: https://orcid.org/0000-0001-7999-9627)
Institutions
- Yanbian University (CN)
- Yanbian University Hospital (CN)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2025-10-17
- DOI
- https://doi.org/10.2174/0113816128395585250923122829
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00