Evaluation of leptin treatment on maintenance of body weight loss in diet‐induced obese mice
Leptin treatment is not sufficient to maintain caloric restriction-induced weight loss in preclinical models and does not support the theory that leptin resistance in obesity is due to excessive leptin production and saturation of leptin signalling.
Authors
- Danna M. Breen (ORCID: https://orcid.org/0000-0002-6460-8555)
- Stephanie Joaquim
- Jimmy Kong
- Rhys D.O. Jones (ORCID: https://orcid.org/0000-0001-5182-0509)
- V. Margaret Jackson (ORCID: https://orcid.org/0000-0002-0079-3915)
- J. Brent Kuzmiski (ORCID: https://orcid.org/0000-0002-9240-4867)
- Ryan Reese
- Kendra K. Bence (ORCID: https://orcid.org/0000-0002-5879-4726)
- John C. Stansfield
- Rocío del M. Saavedra-Peña (ORCID: https://orcid.org/0000-0003-3332-3597)
Institutions
- Pfizer (United States) (US)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1111/dom.70207
- Citations
- 1
- Primary Topic
- Regulation of Appetite and Obesity
- Type
- article
- Field-Weighted Citation Impact
- 0.91