Endoscopic Thulium Laser Ablation with Disitamab Vedotin and Immunotherapy in High-risk Upper Tract Urothelial Carcinoma: A Prospective Pilot Study of a Novel Kidney-sparing Strategy
The combination of endoscopic TLA with perioperative systemic therapy demonstrated promising efficacy and manageable safety in selected patients with localized high-risk UTUC. Our results suggest that there is potential for a paradigm shift in the management of this challenging patient population.
Authors
- Banghua Liao (ORCID: https://orcid.org/0000-0002-1017-4990)
- Hao Zeng (ORCID: https://orcid.org/0000-0002-0483-661X)
- Shuang Zhang (ORCID: https://orcid.org/0000-0002-0047-8456)
- Mengni Zhang (ORCID: https://orcid.org/0000-0002-2906-5161)
- Yige Bao (ORCID: https://orcid.org/0000-0003-4002-5467)
- Yali Shen (ORCID: https://orcid.org/0000-0001-6416-9516)
- Jianjun Ye
- Hao Zhang
- Xinyang Liao (ORCID: https://orcid.org/0000-0002-5216-2752)
- Qiang Wei (ORCID: https://orcid.org/0000-0003-3750-3042)
- Shiyu Zhang (ORCID: https://orcid.org/0000-0002-2536-4324)
- Lei Zheng (ORCID: https://orcid.org/0000-0003-4163-2541)
- Kai Chen (ORCID: https://orcid.org/0000-0003-0193-7949)
- Xiang Li (ORCID: https://orcid.org/0000-0003-0765-1546)
- Zeyu Chen (ORCID: https://orcid.org/0000-0001-8534-0829)
- Xiang Tu
- Peng Zhang (ORCID: https://orcid.org/0000-0001-9004-8144)
- Jiyan Liu (ORCID: https://orcid.org/0000-0003-4885-5481)
- Qihao Wang (ORCID: https://orcid.org/0000-0001-8121-4382)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- European Urology Oncology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1016/j.euo.2025.09.015
- Citations
- 2
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.01