Early Oxygenation and Mortality in Infants Treated with Inhaled Nitric Oxide (iNO) for Persistent Pulmonary Hypertension of the Newborn (PPHN)
Early hypoxemia and severe hyperoxemia were associated with mortality in infants with PPHN. These findings underscore the importance of cautious oxygen titration. Prospective studies are needed to establish optimal oxygen management strategies in this population.
Authors
- Satyan Lakshminrusimha (ORCID: https://orcid.org/0000-0001-6098-2155)
- Marina S. Oren (ORCID: https://orcid.org/0009-0005-3617-2466)
- Kikelomo Babata (ORCID: https://orcid.org/0000-0001-9862-3350)
- June Hu
- Patti J. Burchfield
- Vishal Kapadia (ORCID: https://orcid.org/0000-0001-7862-5869)
- Venkatakrishna Kakkilaya (ORCID: https://orcid.org/0000-0002-5337-5610)
- L. Steven Brown (ORCID: https://orcid.org/0000-0002-0047-5407)
- Michelle Hagans
Institutions
- Parkland Health & Hospital System (US)
- Texas Health Dallas (US)
- UC Davis Children's Hospital (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- The Journal of Pediatrics Clinical Practice
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1016/j.jpedcp.2025.200189
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00