Integrating plasma proteomics and genome-wide association data to identify therapeutic targets for retinal neurodegenerative diseases in Europeans

This study identified six potential protein targets for RND and five existing drugs with therapeutic potential. By integrating plasma proteomics with genetic data, it provides a cost-effective framework for drug discovery.

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Publication Details

Journal
International Journal of Ophthalmology
Published
2025-10-17
DOI
https://doi.org/10.18240/ijo.2025.11.21
Primary Topic
Immune responses and vaccinations
Type
article
Field-Weighted Citation Impact
0.00

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article

Integrating plasma proteomics and genome-wide association data to identify therapeutic targets for retinal neurodegenerative diseases in Europeans

Jing Zhao, Yujin Guo
International Journal of Ophthalmology
Immune responses and vaccinations
article

Integrating plasma proteomics and genome-wide association data to identify therapeutic targets for retinal neurodegenerative diseases in Europeans

Jing Zhao, Yujin Guo
article en

Abstract

This study identified six potential protein targets for RND and five existing drugs with therapeutic potential. By integrating plasma proteomics with genetic data, it provides a cost-effective framework for drug discovery.

International Journal of OphthalmologyVol. 18(11)
Jilin University (CN), First Hospital of Jilin University (CN), Second Affiliated Hospital of Jilin University (CN)
National Natural Science Foundation of China, People's Government of Jilin Province, Education Department of Jilin Province
Openalex Percentile: Top 69%
Immune responses and vaccinations
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