Association of serum bicarbonate with 28-day and 90-day mortality in patients with epilepsy and concurrent sepsis: a retrospective cohort study

Two unique non-liner U-shaped relationships were identified between serum bicarbonate levels and mortality at 28 and 90 days in patients with epilepsy and concurrent sepsis. The lowest mortality rates were observed at approximately 25.0 and 25.9 mEq/L, respectively.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-10-17
DOI
https://doi.org/10.3389/fneur.2025.1608745
Primary Topic
Renal function and acid-base balance
Type
article
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article

Association of serum bicarbonate with 28-day and 90-day mortality in patients with epilepsy and concurrent sepsis: a retrospective cohort study

Y Mao, Qing Hu, Zhihui Li, Yichen Liu et al.
Frontiers in Neurology
Renal function and acid-base balance
article

Association of serum bicarbonate with 28-day and 90-day mortality in patients with epilepsy and concurrent sepsis: a retrospective cohort study

Y Mao, Qing Hu, Zhihui Li, Yichen Liu, Zhixin Li, Shuchang Zhou
article en

Abstract

Two unique non-liner U-shaped relationships were identified between serum bicarbonate levels and mortality at 28 and 90 days in patients with epilepsy and concurrent sepsis. The lowest mortality rates were observed at approximately 25.0 and 25.9 mEq/L, respectively.

Frontiers in NeurologyVol. 16
Beijing Radiation Center (CN), 181st Hospital of Chinese People's Liberation Army (CN)
Openalex Percentile: Top 69%
Renal function and acid-base balance
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