The anti-inflammatory effects of dexamethasone implants in eyes with heavy silicone oil: a prospective study on vitrectomy for diabetic retinopathy
To our knowledge, this first study of dexamethasone implants with HSO in PDR suggests intraoperative DEX may be a safe, potentially beneficial adjunct for diabetic TRD undergoing phacoemulsification plus vitrectomy with HSO, reducing inflammation and number of anti-VEGF injections over 3 months, and offering useful directions for future research in this preliminary prospective evaluation overall.
Authors
- Simin Xu (ORCID: https://orcid.org/0000-0003-1181-5937)
- Junliang Dong (ORCID: https://orcid.org/0000-0003-3109-185X)
- Haomin Lu
- Yan Zhang (ORCID: https://orcid.org/0000-0002-9173-7029)
- Xingguo Zhang (ORCID: https://orcid.org/0000-0001-8390-642X)
- Dawei Sun
- Bo Jiang (ORCID: https://orcid.org/0009-0000-7425-5717)
- Minghao Sun (ORCID: https://orcid.org/0000-0002-1657-0740)
Institutions
- Harbin Medical University (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.3389/fendo.2025.1673884
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00