Rapidly progressive anti-GBM disease secondary to long-standing rheumatoid arthritis: a case report and literature review
This case highlights the need for early serological testing for anti-GBM disease in RA patients with unexplained hematuria/proteinuria and for immunosuppressive therapy mindful of infection risk. Additionally, our literature review identified only ten reported cases of RA with anti-GBM disease, highlighting the rarity of this condition.
Authors
- Qian Guo (ORCID: https://orcid.org/0000-0002-2133-5358)
- Yadan Zou
- Jing Zhang (ORCID: https://orcid.org/0000-0001-9617-9305)
- Lina Zhang (ORCID: https://orcid.org/0000-0003-3890-8690)
- Yanfeng Zhang (ORCID: https://orcid.org/0000-0003-1319-3270)
- Sheng‐Guang Li (ORCID: https://orcid.org/0000-0002-8047-9984)
- Jing Xu (ORCID: https://orcid.org/0000-0002-0147-0608)
- Ting Long (ORCID: https://orcid.org/0000-0002-9108-4873)
- Ruohan Yu
- Li Ji (ORCID: https://orcid.org/0000-0001-7500-0660)
Institutions
- Peking University (CN)
- Peking University International Hospital (CN)
- Peking University Shougang Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.3389/fimmu.2025.1661117
- Primary Topic
- Peripheral Neuropathies and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00