Three years of remote electrical neuromodulation (REN) acute treatment for migraine shows consistent effectiveness and no tachyphylaxis phenomenon
This study demonstrates the long-term safety, consistent utilization, and acute treatment effectiveness, with no tachyphylaxis, in patients with migraine consistently treating with REN for 3 years. This suggests that REN offers an effective, well-tolerated, safe, and sustainable long-term treatment option for individuals with migraine.
Authors
- Alon Ironi (ORCID: https://orcid.org/0000-0002-3992-4978)
- Marius Birlea (ORCID: https://orcid.org/0000-0002-4663-2084)
- Alit Stark‐Inbar (ORCID: https://orcid.org/0000-0001-6434-6447)
- Stephanie J. Nahas (ORCID: https://orcid.org/0000-0001-8846-8393)
- Sharon Shmuely (ORCID: https://orcid.org/0000-0001-9413-6125)
- Alan M. Rapoport (ORCID: https://orcid.org/0000-0002-6311-8562)
- William B. Young (ORCID: https://orcid.org/0000-0002-8036-3666)
- Eden Mama (ORCID: https://orcid.org/0009-0000-5076-7427)
Institutions
- Thomas Jefferson University (US)
- University of California, Los Angeles (US)
- University of Colorado Anschutz Medical Campus (US)
- Netanya Academic College (IL)
- University of Colorado Denver (US)
Publication Details
- Journal
- Headache The Journal of Head and Face Pain
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1111/head.15069
- Citations
- 1
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47