Subtype-specific NK cell-TAM interactions drive a novel prognostic signature in HNSCC
This study uncovers subtype-specific NK-TAM interactions in HNSCC and introduces CINT as a robust prognostic and immunotherapy response model, offering a new strategy for immune microenvironment-targeted therapy.
Authors
- Xuejiao Han (ORCID: https://orcid.org/0000-0002-9842-8990)
- Huan Li (ORCID: https://orcid.org/0000-0003-2168-3579)
- Jianhua Wei (ORCID: https://orcid.org/0000-0002-4900-8631)
- Yaodong He (ORCID: https://orcid.org/0000-0003-0961-4079)
- Yan Wang (ORCID: https://orcid.org/0000-0002-6116-109X)
- Yun Li (ORCID: https://orcid.org/0000-0001-8414-2724)
- Zhenyan Zhao
- Yating Hu (ORCID: https://orcid.org/0000-0003-2946-1006)
- Yanbing Yao
Institutions
- Air Force Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.3389/fimmu.2025.1676878
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00