Lacticaseibacillus rhamnosus CBT LR5 with skim milk alleviates scopolamine-induced cognitive impairment in mice
Collectively, these findings suggest that the synergistic effects of <i>L. rhamnosus</i> CBT LR5 combined with skim milk may represent an effective dietary intervention for cognitive enhancement, potentially through gut microbiota modulation, improved barrier integrity, reduced inflammation, and enhanced neurotrophic signaling.
Authors
- Sung Sam Lim (ORCID: https://orcid.org/0000-0003-2361-0787)
- Kyohee Cho (ORCID: https://orcid.org/0000-0002-4595-8701)
- Sanghyun Lim (ORCID: https://orcid.org/0000-0003-3422-3766)
- Soo-Hyun Sung (ORCID: https://orcid.org/0000-0001-7606-0147)
- Ye Eun Cho
- Song-In Kim (ORCID: https://orcid.org/0000-0001-6785-3196)
- So-Yeon Kim (ORCID: https://orcid.org/0000-0002-2120-0226)
- Se Jin Park (ORCID: https://orcid.org/0000-0002-1618-5906)
- Ho Jung Bae
Institutions
- Kangwon National University (KR)
- Changwon National University (KR)
- Cell Biotech (South Korea) (KR)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.3389/fmicb.2025.1672153
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Agriculture, Food and Rural Affairs
- Ministry of Science and ICT, South Korea
- Commercializations Promotion Agency for R and D Outcomes
- Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry