GEODE: an in silico tool that translates in vitro to in vivo predictions of tuberculosis antibiotic combination efficacy
This work provides a novel tool that can be used to quickly and efficiently evaluate drug regimens for TB.
Authors
- H. Jacob Borish (ORCID: https://orcid.org/0000-0002-9220-673X)
- Talia Greenstein (ORCID: https://orcid.org/0000-0002-2710-602X)
- Philana Ling Lin (ORCID: https://orcid.org/0000-0001-5169-3714)
- Mark Rodgers (ORCID: https://orcid.org/0000-0002-5196-9239)
- Jaime Tomko (ORCID: https://orcid.org/0000-0002-9308-4957)
- Pauline A Maiello (ORCID: https://orcid.org/0000-0002-5188-8420)
- Bree B. Aldridge (ORCID: https://orcid.org/0000-0003-2236-1424)
- Denise E. Kirschner (ORCID: https://orcid.org/0000-0002-1053-2591)
- Harris B. Chishti
- Maral Budak (ORCID: https://orcid.org/0000-0002-7934-4230)
- Kara Kracinovsky
- JoAnne L. Flynn
- Mariana Pereira Moraes (ORCID: https://orcid.org/0009-0004-0962-2620)
Institutions
- Tufts University (US)
- University of Pittsburgh (US)
- University of Michigan (US)
- Children's Hospital of Pittsburgh (US)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.3389/fphar.2025.1639673
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.40