Low rate of infectious mortality omitting fluoroquinolone prophylaxis in high-risk hematological patients, a single centre experience
Although our cohort was small, our results advocate for the exclusion of FQ prophylaxis in HR hematological patients, without increasing the IRM rate and addressing the risk of life-threatening MDR infections. While we believe it is mandatory to have an efficient protocol for the prompt treatment of FN, our data should encourage hematologists to limit the use of FQ prophylaxis.
Authors
- Monica Bocchia (ORCID: https://orcid.org/0000-0003-3538-3913)
- Elisabetta Zappone (ORCID: https://orcid.org/0000-0002-4276-0214)
- Margherita Malchiodi
- Corrado Zuanelli Brambilla (ORCID: https://orcid.org/0000-0002-6396-2990)
- Alessandra Cartocci (ORCID: https://orcid.org/0000-0002-1818-6275)
- Marzia Defina
- Mario Tumbarello (ORCID: https://orcid.org/0000-0002-9519-8552)
- Anna Sicuranza (ORCID: https://orcid.org/0000-0002-5840-2956)
- Paola Pacelli (ORCID: https://orcid.org/0000-0001-5838-1123)
- Adele Santoni (ORCID: https://orcid.org/0009-0006-9848-645X)
Institutions
- University of Siena (IT)
- Azienda Ospedaliera Universitaria Senese (IT)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.3389/fmicb.2025.1632055
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00