Masked formylation of activated aromatics <i>via</i> dithianes and a mild, sustainable cleavage protocol
Masked formylation using dithiane oxide activated by oxalyl chloride via a thionium ion. It enables efficient substitution in electron-rich arenes and mild dithiane cleavage to aldehydes, offering a simple, versatile alternative to classical methods.
Authors
- Diego Gamba‐Sánchez (ORCID: https://orcid.org/0000-0001-5432-5108)
- Mario A. Macías (ORCID: https://orcid.org/0000-0003-2749-8489)
- Camilo Mahecha‐Mahecha (ORCID: https://orcid.org/0000-0002-0034-1169)
- Julia Urbiña-Alvarez
- Daniela Torres-Ruiz
- Gabriel Hernandez-Abdallah
Institutions
- Universidad de Los Andes (CO)
- Laboratoire de Synthèse Organique (FR)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1039/d5qo01300c
- Primary Topic
- Asymmetric Hydrogenation and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00