Altered Cortical Gyrification Is Associated with Cortical and White Matter Microstructure in Individuals with Early Psychosis: A Multimodal Neuroimaging Study

We present the first in vivo evidence that anomalies in cortical folding may be linked to alterations in both the underlying cortical cytoarchitecture and associated microstructure of ipsilateral long-range white matter connections in psychosis.

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Publication Details

Journal
Schizophrenia Bulletin
Published
2025-10-17
DOI
https://doi.org/10.1093/schbul/sbaf172
Primary Topic
Advanced Neuroimaging Techniques and Applications
Type
article
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article

Altered Cortical Gyrification Is Associated with Cortical and White Matter Microstructure in Individuals with Early Psychosis: A Multimodal Neuroimaging Study

Michael J. Coleman, Sylvain Bouix, Daiki Sasabayashi, Daphne J. Holt et al.
Schizophrenia Bulletin
Advanced Neuroimaging Techniques and Applications
article

Altered Cortical Gyrification Is Associated with Cortical and White Matter Microstructure in Individuals with Early Psychosis: A Multimodal Neuroimaging Study

Michael J. Coleman, Sylvain Bouix, Daiki Sasabayashi, Daphne J. Holt, Marek Kubicki, Döst Öngür, Anastasia Haidar, Tsutomu Takahashi, Tashrif Billah, Yoji Hirano, Yogesh Rathi, Kathryn E. Lewandowski, Shinsuke Koike, Raquelle I. Mesholam‐Gately, Moritz Haaf, Cornelius Berberich, Michio Suzuki, Johanna Seitz‐Holland, Grace R. Jacobs, Elana Kotler, Kang Ik K. Cho, Nicholas Kim, Matcheri S. Keshavan, Joanne Wojcik, Alan Breier, Martha E. Shenton, Ofer Pasternak, Suheyla Cetin-Karayumak, Dheshan Mohandass
article en

Abstract

We present the first in vivo evidence that anomalies in cortical folding may be linked to alterations in both the underlying cortical cytoarchitecture and associated microstructure of ipsilateral long-range white matter connections in psychosis.

Schizophrenia Bulletin
University of Miyazaki (JP), Brigham and Women's Hospital (US), Beth Israel Deaconess Medical Center (US), Harvard University (US), Université du Québec à Montréal (CA), Universität Hamburg (DE), McLean Hospital (US), Massachusetts General Hospital (US), University Medical Center Hamburg-Eppendorf (DE), University of Toyama (JP), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US), Advanced Institute of Industrial Technology (JP), The University of Tokyo (JP), École de Technologie Supérieure (CA)
Openalex Percentile: Top 57%
Advanced Neuroimaging Techniques and Applications
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