CRYSTALLBrain: crystalloid fluid choice and neurological outcome in patients with non-traumatic subarachnoid haemorrhage—a study protocol for a multi-centre randomised double-blind clinical trial
The trial is registered on ClinicalTrials.gov (date of registration 18 June 2021) and on the Swiss National Clinical Trials Portal, SNCTP000004575.
Authors
- Hervé Quintard (ORCID: https://orcid.org/0000-0002-3870-6370)
- Martín Müller (ORCID: https://orcid.org/0000-0003-4067-7174)
- Urs Pietsch (ORCID: https://orcid.org/0000-0001-6957-2638)
- Miodrag Filipovic (ORCID: https://orcid.org/0000-0003-1764-7145)
- Joerg C. Schefold (ORCID: https://orcid.org/0000-0001-9162-5724)
- Carmen Andrea Pfortmueller (ORCID: https://orcid.org/0000-0003-0326-2770)
- Anna S. Messmer (ORCID: https://orcid.org/0000-0002-3206-9112)
- Werner Josef Z'Graggen (ORCID: https://orcid.org/0000-0002-5684-4419)
- Stephan M. Jakob (ORCID: https://orcid.org/0000-0002-2195-0473)
- Matthieu Pitteloud
Institutions
- University of Bern (CH)
- University of St.Gallen (CH)
- University Hospital of Bern (CH)
- University Hospital of Geneva (CH)
Publication Details
- Journal
- Trials
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1186/s13063-025-09099-9
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Bern
- Intensive Care Foundation
- Inselspital, Universitätsspital Bern