Retinoblastoma survival trend: a 30-year analysis from a referral single center in Iran
This study revealed that Introduction of systemic chemotherapy as mainstay of Rb treatment, has led to a significant reduction in mortality and morbidity rates. The incorporation of targeted chemotherapy has further decreased the need for enucleation, but it has not substantially impacted the mortality rate. Unfortunately, in spite of reduction trend in enucleation, systemic and targeted chemotherapy was unable to save the affected globe in nearly half of the patients, even when the malignancy was diagnosed in the earlier stages.
Authors
- Reza Mirshahi (ORCID: https://orcid.org/0000-0002-5997-6417)
- Ahad Sedaghat (ORCID: https://orcid.org/0000-0002-4701-1933)
- Parya Abdolalizadeh (ORCID: https://orcid.org/0000-0002-7420-7448)
- Masood Naseripour (ORCID: https://orcid.org/0000-0003-1217-3470)
- Hengameh Kasraei (ORCID: https://orcid.org/0000-0002-3989-4430)
- Samira Chaibakhsh (ORCID: https://orcid.org/0000-0001-9462-118X)
- Ali Aghajani
- Mohammadreza Fazel
Institutions
- Isfahan University of Medical Sciences (IR)
- Iran University of Medical Sciences (IR)
- Urmia University (IR)
- Kowsar Hospital (IR)
- Shaheed Rajaei Cardiovascular Medical and Research Center (IR)
Publication Details
- Journal
- International Journal of Retina and Vitreous
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1186/s40942-025-00702-4
- Citations
- 1
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71