The expression of miR-381-3p in acute myeloid leukemia and its effect on corresponding cell proliferation and apoptosis
miR-381-3p is low expressed in AML patients, and its overexpression can significantly prolong OS and PFS. miR-381-3p can promote apoptosis of AML cells, inhibit proliferation, and may become a targeted molecule for the treatment of AML.
Authors
- Hongxia Zhang (ORCID: https://orcid.org/0000-0002-8358-8617)
- Peixin Zhang (ORCID: https://orcid.org/0000-0002-5436-4817)
- Jiali Hu (ORCID: https://orcid.org/0009-0007-2469-5520)
Institutions
- First Affiliated Hospital of Shihezi University Medical College (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1007/s12672-025-03743-1
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00