Risk factors of COVID-19 breakthrough infection: a case-control test-negative design study

The probability of breakthrough SARS-CoV-2 infection was significantly higher in hospitalized patients who had received their last vaccine dose more than six months before hospitalization; while immunosuppression was the most important risk factor for breakthrough infection.

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Publication Details

Journal
BMC Infectious Diseases
Published
2025-10-17
DOI
https://doi.org/10.1186/s12879-025-11773-x
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
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article

Risk factors of COVID-19 breakthrough infection: a case-control test-negative design study

Oleguer Parés‐Badell, Laia Pinós, Cristina Andrés, Andrés Antón et al.
BMC Infectious Diseases
SARS-CoV-2 and COVID-19 Research
article

Risk factors of COVID-19 breakthrough infection: a case-control test-negative design study

Oleguer Parés‐Badell, Laia Pinós, Cristina Andrés, Andrés Antón, Blanca Borràs-Bermejo, Susana Otero-Romero, Gabriela Tejada-Panduro, Ingrid Carbones
article en

Abstract

The probability of breakthrough SARS-CoV-2 infection was significantly higher in hospitalized patients who had received their last vaccine dose more than six months before hospitalization; while immunosuppression was the most important risk factor for breakthrough infection.

BMC Infectious DiseasesVol. 25(1)
Hebron University (PS), Instituto de Salud Carlos III (ES), Vall d'Hebron Institut de Recerca (ES), Vall d'Hebron Hospital Universitari (ES), Instituto de Investigación de Enfermedades Raras (ES)
Openalex Percentile: Top 65%
SARS-CoV-2 and COVID-19 Research
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