Atypical Koebner Response: Psoriasis Remission Following Endovenous Laser Ablation for Venous Insufficiency: A Novel Case Report and Literature Review

Psoriasis, a chronic inflammatory skin disease, presents treatment challenges, especially when complicated by conditions like venous insufficiency. While the Koebner phenomenon suggests trauma can worsen psoriasis, this case report describes a 41-year-old male patient with psoriasis vulgaris and venous insufficiency, who experienced complete remission of his psoriasis following endovenous laser ablation for his varicose veins. This unexpected outcome, beginning within weeks of the procedure and culminating in complete remission within 6 months, highlights the complex relationship between trauma and psoriasis. Potential explanations include a localised immune response, improved circulation, or a direct laser effect. This case underscores the need for further research into the interplay between venous insufficiency treatments and psoriasis activity, as understanding these mechanisms could inform future treatment strategies.

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Publication Details

Journal
EMJ Dermatology
Published
2025-10-17
DOI
https://doi.org/10.33590/emjdermatol/lrji6587
Primary Topic
Diagnosis and Treatment of Venous Diseases
Type
article
Field-Weighted Citation Impact
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article

Atypical Koebner Response: Psoriasis Remission Following Endovenous Laser Ablation for Venous Insufficiency: A Novel Case Report and Literature Review

Gökhan Arslan, Yiğit Tokgöz
EMJ Dermatology
Diagnosis and Treatment of Venous Diseases
article

Atypical Koebner Response: Psoriasis Remission Following Endovenous Laser Ablation for Venous Insufficiency: A Novel Case Report and Literature Review

Gökhan Arslan, Yiğit Tokgöz
article en

Abstract

Psoriasis, a chronic inflammatory skin disease, presents treatment challenges, especially when complicated by conditions like venous insufficiency. While the Koebner phenomenon suggests trauma can worsen psoriasis, this case report describes a 41-year-old male patient with psoriasis vulgaris and venous insufficiency, who experienced complete remission of his psoriasis following endovenous laser ablation for his varicose veins. This unexpected outcome, beginning within weeks of the procedure and culminating in complete remission within 6 months, highlights the complex relationship between trauma and psoriasis. Potential explanations include a localised immune response, improved circulation, or a direct laser effect. This case underscores the need for further research into the interplay between venous insufficiency treatments and psoriasis activity, as understanding these mechanisms could inform future treatment strategies.

EMJ Dermatology
University of Health Science (KH), Sağlık Bilimleri Üniversitesi (TR)
Openalex Percentile: Top 54%
Diagnosis and Treatment of Venous Diseases
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Atypical Koebner Response: Psoriasis Remission Following Endovenous Laser Ablation for Venous Insufficiency: A Novel Case Report and Literature Review — Gökhan Arslan, Yiğit Tokgöz · EMJ Dermatology (2025) | TGRS Research Map | TGRS