High-Sensitivity Terahertz Biosensor Based on a Multi-Layer Hybrid Structure Consisting of a Defect Mode and Graphene

A high-sensitivity terahertz (THz) biosensor is proposed in this paper based on a multi-layer hybrid structure consisting of a defect mode and graphene with a truncation layer. This biosensor is based on symmetrical Bragg reflectors with a defect layer and graphene with a truncation layer, which effectively comprise a multi-layer hybrid resonance excitation structure. The high sensitivity of this biosensor is developed through defect mode resonance, and the resonance reflection peak is made sharper and more sensitive by using graphene with a truncation layer. After testing and analysis, the sensitivity of this biosensor structure is greatly affected by the refractive index and thickness of the sensing medium. By setting parameters appropriately, the composite structure can be used as both a liquid biosensor and a gas biosensor, the maximum sensitivity of which can surpass 2000°/RIU, while an FOM value of 22,500 RIU<sup>-1</sup> can be achieved. At the same time, when the refractive index of the liquid sensing medium changes to 0.01 relative to water (the same applies to changes in the gas sensing medium), the sensitivity of this structure still exceeds 600°/RIU, demonstrating that this biosensor has advantages including high sensitivity, a high FOM, wide applicability, and slow sensitivity attenuation. Therefore, the sensing scheme proposed in this paper has potential application prospects in the field of biosensing based on micro/nanostructures due to its simple structure, low requirements for processing conditions, and high sensitivity.

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Publication Details

Journal
Biosensors
Published
2025-10-17
DOI
https://doi.org/10.3390/bios15100702
Primary Topic
Plasmonic and Surface Plasmon Research
Type
article
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article

High-Sensitivity Terahertz Biosensor Based on a Multi-Layer Hybrid Structure Consisting of a Defect Mode and Graphene

Zhengchun Zhao, Hai Hu, Shangkun Mo, Yangbao Deng
Biosensors
Plasmonic and Surface Plasmon Research
article

High-Sensitivity Terahertz Biosensor Based on a Multi-Layer Hybrid Structure Consisting of a Defect Mode and Graphene

Zhengchun Zhao, Hai Hu, Shangkun Mo, Yangbao Deng
article en

Abstract

A high-sensitivity terahertz (THz) biosensor is proposed in this paper based on a multi-layer hybrid structure consisting of a defect mode and graphene with a truncation layer. This biosensor is based on symmetrical Bragg reflectors with a defect layer and graphene with a truncation layer, which effectively comprise a multi-layer hybrid resonance excitation structure. The high sensitivity of this biosensor is developed through defect mode resonance, and the resonance reflection peak is made sharper and more sensitive by using graphene with a truncation layer. After testing and analysis, the sensitivity of this biosensor structure is greatly affected by the refractive index and thickness of the sensing medium. By setting parameters appropriately, the composite structure can be used as both a liquid biosensor and a gas biosensor, the maximum sensitivity of which can surpass 2000°/RIU, while an FOM value of 22,500 RIU<sup>-1</sup> can be achieved. At the same time, when the refractive index of the liquid sensing medium changes to 0.01 relative to water (the same applies to changes in the gas sensing medium), the sensitivity of this structure still exceeds 600°/RIU, demonstrating that this biosensor has advantages including high sensitivity, a high FOM, wide applicability, and slow sensitivity attenuation. Therefore, the sensing scheme proposed in this paper has potential application prospects in the field of biosensing based on micro/nanostructures due to its simple structure, low requirements for processing conditions, and high sensitivity.

BiosensorsVol. 15(10)
Hunan City University (CN)
Openalex Percentile: Top 71%
Plasmonic and Surface Plasmon Research
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