Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid, which are reported to function as chelating agents in cosmetic products. The Panel reviewed the available data to determine the safety of these ingredients. The Panel concluded that Tetrasodium Glutamate Diacetate is safe in cosmetics in the practices of use and concentration described in this safety assessment, and that the available data are insufficient to make a determination that Beta-Alanine Diacetic Acid is safe under the intended conditions of use in cosmetic formulations.
Authors
- Paul W. Snyder (ORCID: https://orcid.org/0000-0002-0444-2426)
- Monice M. Fiume
- D. Belsito (ORCID: https://orcid.org/0000-0003-1229-6673)
- Ronald C. Shank
- Lisa A. Peterson (ORCID: https://orcid.org/0000-0001-8715-4480)
- D.C. Liebler (ORCID: https://orcid.org/0000-0002-7873-3031)
- Bart A. Heldreth (ORCID: https://orcid.org/0000-0001-8597-0855)
- Thomas J. Slaga
- Wilma Fowler Bergfeld (ORCID: https://orcid.org/0000-0002-5981-3925)
- Curtis D. Klaassen (ORCID: https://orcid.org/0000-0003-3408-6191)
- Christina L. Burnett
- David E. Cohen
- James G. Marks
Publication Details
- Journal
- International Journal of Toxicology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1177/10915818251344597
- Primary Topic
- Contact Dermatitis and Allergies
- Type
- article
- Field-Weighted Citation Impact
- 0.00