When Common Tumours Hide in Uncommon Places: Paediatric Sacral Ewing Sarcoma With Metastases

Ewing's sarcoma is a highly aggressive malignant small round blue cell tumour that typically affects the long bones and axial skeleton in children and adolescents. Sacral involvement is uncommon, often leading to diagnostic delays due to nonspecific symptoms. We report a case of a nine-year-old girl presenting with chronic back pain and weight loss, eventually found to have a large sacral mass with hepatic metastases. Imaging revealed a destructive presacral tumour with soft tissue extension, and histopathology confirmed Ewing's sarcoma with EWSR1 rearrangement. This case highlights the diagnostic challenges of rare anatomical sites, emphasises the value of multimodality imaging, and reinforces the importance of including Ewing's sarcoma in the differential for persistent paediatric back pain.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2025-10-17
DOI
https://doi.org/10.7759/cureus.94789
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

When Common Tumours Hide in Uncommon Places: Paediatric Sacral Ewing Sarcoma With Metastases

Audrey R Rumhumha, Nabeela Kazee, Mantsane Mokone
Cureus
Sarcoma Diagnosis and Treatment
article

When Common Tumours Hide in Uncommon Places: Paediatric Sacral Ewing Sarcoma With Metastases

Audrey R Rumhumha, Nabeela Kazee, Mantsane Mokone
article en

Abstract

Ewing's sarcoma is a highly aggressive malignant small round blue cell tumour that typically affects the long bones and axial skeleton in children and adolescents. Sacral involvement is uncommon, often leading to diagnostic delays due to nonspecific symptoms. We report a case of a nine-year-old girl presenting with chronic back pain and weight loss, eventually found to have a large sacral mass with hepatic metastases. Imaging revealed a destructive presacral tumour with soft tissue extension, and histopathology confirmed Ewing's sarcoma with EWSR1 rearrangement. This case highlights the diagnostic challenges of rare anatomical sites, emphasises the value of multimodality imaging, and reinforces the importance of including Ewing's sarcoma in the differential for persistent paediatric back pain.

CureusVol. 17(10)
University of the Witwatersrand (ZA)
Openalex Percentile: Top 58%
Sarcoma Diagnosis and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.