Linoleic Acid and Linolenic Acid May Alleviate Heart Failure Through Aquaporin (AQP1) and Gut Microbiota
LA and ALA alleviate CHF through an AQP1-dependent reduction in myocardial edema and AQP1-independent anti-inflammatory and gut microbiota-modulating effects. These findings highlight their potential as a multi-target therapeutic complex for CHF.
Authors
- Yi-Han Li
- Y Y Liu (ORCID: https://orcid.org/0000-0001-8514-5871)
- Haotian Li (ORCID: https://orcid.org/0009-0003-9755-1772)
- Qing Miao (ORCID: https://orcid.org/0000-0003-2478-9846)
- Jianqin Yang (ORCID: https://orcid.org/0000-0001-9949-4247)
- Y.M. Song (ORCID: https://orcid.org/0009-0008-7106-1421)
Institutions
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Foods
- Published
- 2025-10-17
- DOI
- https://doi.org/10.3390/foods14203541
- Citations
- 1
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 1.39