The Medication Patterns of Spinocerebellar Ataxia Type 3 Mutation Carriers Enrolled in the ESMI Cohort
This is the first study to explore medication usage patterns in SCA3 mutation carriers. Our study provides a comprehensive overview of the medications administered in SCA3 and underscores the importance of collaborative efforts toward achieving standardized clinical practices in the management of this disease.
Authors
- Héctor García‐Moreno (ORCID: https://orcid.org/0000-0002-0697-3271)
- Paula Pires (ORCID: https://orcid.org/0009-0008-2370-1666)
- João Vasconcelos (ORCID: https://orcid.org/0000-0002-5866-7460)
- Bart P.C. van de Warrenburg (ORCID: https://orcid.org/0000-0003-4412-1616)
- Manuela Lima (ORCID: https://orcid.org/0000-0002-3357-3273)
- Jon Infante (ORCID: https://orcid.org/0000-0003-4025-4606)
- Pedro Lopes (ORCID: https://orcid.org/0000-0001-8450-8642)
- Mafalda Raposo (ORCID: https://orcid.org/0000-0001-6899-0352)
- Luís Pereira de Almeida (ORCID: https://orcid.org/0000-0001-5831-3307)
- Ana Paula Rosa (ORCID: https://orcid.org/0000-0002-8718-1582)
- João Durães (ORCID: https://orcid.org/0000-0001-9671-593X)
- Magda M. Santana (ORCID: https://orcid.org/0000-0003-4076-7516)
- Kathrin Reetz (ORCID: https://orcid.org/0000-0002-9730-9228)
- Cristina Januário (ORCID: https://orcid.org/0000-0001-5402-3978)
- Inês Cunha (ORCID: https://orcid.org/0000-0003-3059-4068)
- Pedro Coelho (ORCID: https://orcid.org/0000-0003-0515-9187)
- Cristina Gonzalez‐Robles (ORCID: https://orcid.org/0000-0001-6809-0127)
- Ana F. Ferreira (ORCID: https://orcid.org/0000-0001-9839-3364)
- Paola Giunti (ORCID: https://orcid.org/0000-0003-3508-4788)
- Jennifer Faber (ORCID: https://orcid.org/0000-0003-3265-0262)
- Dagmar Timmann (ORCID: https://orcid.org/0000-0003-1935-416X)
- Laetitia S. Gaspar (ORCID: https://orcid.org/0000-0001-9262-845X)
- Heike Jacobi
- Luís Teves (ORCID: https://orcid.org/0000-0002-5555-5615)
- Friedrich Erdlenbruch (ORCID: https://orcid.org/0009-0006-0654-836X)
- Andreas Gustafsson Thieme (ORCID: https://orcid.org/0000-0001-6221-8601)
- Ludger J. Schöls (ORCID: https://orcid.org/0000-0001-7774-5025)
- João Lemos (ORCID: https://orcid.org/0000-0002-9128-7064)
- Lukas Beichert (ORCID: https://orcid.org/0009-0000-9259-9230)
- Carlos González (ORCID: https://orcid.org/0000-0001-8796-1282)
- Patrick Silva (ORCID: https://orcid.org/0000-0002-5436-8949)
- Joana Ribeiro
- Jeannette Hübener‐Schmid (ORCID: https://orcid.org/0000-0002-4973-0923)
- Bárbara Oliveiros
- Thomas Klockgether
- Jeroen J. de Vries (ORCID: https://orcid.org/0000-0002-7534-4161)
- Teresa Kay (ORCID: https://orcid.org/0000-0003-3622-2281)
- M Costa (ORCID: https://orcid.org/0009-0001-2885-1769)
Institutions
- Universidade dos Açores (PT)
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- Universidade do Porto (PT)
- Heidelberg University (DE)
- University Hospital Bonn (DE)
- German Center for Neurodegenerative Diseases (DE)
- Hospitais da Universidade de Coimbra (PT)
- University Hospital Heidelberg (DE)
- Radboud University Medical Center (NL)
- Biomedical Research Networking Center on Neurodegenerative Diseases (ES)
- Instituto de Investigación Marqués de Valdecilla (ES)
- Gene PreDiT (Portugal) (PT)
- Centro de Investigación Biomédica en Red (ES)
- Universitätsklinikum Aachen (DE)
- Hertie Institute for Clinical Brain Research (DE)
- National Hospital for Neurology and Neurosurgery (GB)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
- Institute for Biotechnology and Bioengineering (PT)
- University College London (GB)
- University of Coimbra (PT)
- University of Tübingen (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- CNS Drugs
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1007/s40263-025-01237-w
- Primary Topic
- Genetic Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Friedreich's Ataxia Research Alliance
- National Ataxia Foundation
- Fundo Regional para a Ciência e Tecnologia
- EU Joint Programme – Neurodegenerative Disease Research
- European Federation of Pharmaceutical Industries and Associations
- National Institute for Health and Care Research
- University College London
- European Commission
- Deutsche Forschungsgemeinschaft
- ZonMw
- Bundesministerium für Bildung und Forschung
- Else Kröner-Fresenius-Stiftung
- RWTH Aachen University
- Hersenstichting
- University College London Hospitals NHS Foundation Trust
- Programa Operacional Regional do Centro
- HORIZON EUROPE Framework Programme
- Medical Research Council
- Fundação para a Ciência e a Tecnologia
- European Regional Development Fund
- Medizinische Fakultät, RWTH Aachen University