Pleiotrophin modulates cell proliferation, prostate smooth muscle contraction and fibrosis in hyperplastic prostate
Our current study demonstrates that PTN is of significance in the onset and development of BPH and may be a new target for the treatment of BPH.
Authors
- Jiang Liu (ORCID: https://orcid.org/0000-0002-4409-1157)
- Yiqiao Zhao (ORCID: https://orcid.org/0000-0001-7109-9536)
- Min-Liang Cheng
- Xun Fu (ORCID: https://orcid.org/0000-0001-9180-364X)
- Ping Chen (ORCID: https://orcid.org/0000-0003-0427-2428)
- Yuming Guo (ORCID: https://orcid.org/0000-0002-2351-4456)
- Mingzhe Chen (ORCID: https://orcid.org/0000-0003-2570-703X)
- Michael E. DiSanto (ORCID: https://orcid.org/0000-0003-4754-7794)
- Huan Liu (ORCID: https://orcid.org/0000-0001-5604-9047)
- Yong Li (ORCID: https://orcid.org/0000-0002-4108-0989)
- Xinhua Zhang (ORCID: https://orcid.org/0000-0003-0267-428X)
- Jianmin Liu (ORCID: https://orcid.org/0000-0001-7009-3116)
- Yan Li (ORCID: https://orcid.org/0000-0003-1644-2308)
- Zhonghua Wu (ORCID: https://orcid.org/0000-0002-5674-2471)
- Jiuming Fan
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Wuhan University (CN)
- Henan University Huaihe Hospital and Huaihe Clinical Institute (CN)
- Cooper Medical School of Rowan University (US)
- Zhongnan Hospital of Wuhan University (CN)
- Jingning County People's Hospital (CN)
- Hubei University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1186/s12967-025-07172-0
- Primary Topic
- Proteoglycans and glycosaminoglycans research
- Type
- article
- Field-Weighted Citation Impact
- 0.00