Pleiotrophin modulates cell proliferation, prostate smooth muscle contraction and fibrosis in hyperplastic prostate

Our current study demonstrates that PTN is of significance in the onset and development of BPH and may be a new target for the treatment of BPH.

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Publication Details

Journal
Journal of Translational Medicine
Published
2025-10-17
DOI
https://doi.org/10.1186/s12967-025-07172-0
Primary Topic
Proteoglycans and glycosaminoglycans research
Type
article
Field-Weighted Citation Impact
0.00
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article

Pleiotrophin modulates cell proliferation, prostate smooth muscle contraction and fibrosis in hyperplastic prostate

Jiang Liu, Yiqiao Zhao, Min-Liang Cheng, Xun Fu et al.
Journal of Translational Medicine
Proteoglycans and glycosaminoglycans research
article

Pleiotrophin modulates cell proliferation, prostate smooth muscle contraction and fibrosis in hyperplastic prostate

Jiang Liu, Yiqiao Zhao, Min-Liang Cheng, Xun Fu, Ping Chen, Yuming Guo, Mingzhe Chen, Michael E. DiSanto, Huan Liu, Yong Li, Xinhua Zhang, Jianmin Liu, Yan Li, Zhonghua Wu, Jiuming Fan
article en

Abstract

Our current study demonstrates that PTN is of significance in the onset and development of BPH and may be a new target for the treatment of BPH.

Journal of Translational MedicineVol. 23(1)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), Wuhan University (CN), Henan University Huaihe Hospital and Huaihe Clinical Institute (CN), Cooper Medical School of Rowan University (US), Zhongnan Hospital of Wuhan University (CN), Jingning County People's Hospital (CN), Hubei University (CN)
Openalex Percentile: Top 69%
Proteoglycans and glycosaminoglycans research
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