Immunogenic cell death-inducing Rh( <scp>i</scp> ) and Ir( <scp>i</scp> ) complexes with bis(imino)acenaphthene-derived ligands: insights into the role of the metal center and the ligands
The Rh( i ) complex 3a with the 1,2-bis[(2,6-diisopropylphenyl)imino]acenaphthene (dpp-bian) ligand induces type I immunogenic cell death (ICD), whereas the analogous Ir( i ) complex does not, revealing metal-specific immunogenicity.
Authors
- V. I. Komlyagina
- Nikolay Filippovich Romashev
- Iakov S. Fomenko⧫ (ORCID: https://orcid.org/0000-0001-7916-5008)
- Taotao Zou (ORCID: https://orcid.org/0000-0001-9129-4398)
- Maria V. Babak (ORCID: https://orcid.org/0000-0002-2009-7837)
- Artem L. Gushchin (ORCID: https://orcid.org/0000-0003-3214-1433)
- Tamara Petrović (ORCID: https://orcid.org/0000-0003-1818-8710)
- Pavel A. Abramov⧫ (ORCID: https://orcid.org/0000-0003-4479-5100)
- Ivan V. Bakaev⧫ (ORCID: https://orcid.org/0009-0000-7203-1840)
- Alexey A. Ryadun (ORCID: https://orcid.org/0000-0001-5091-7720)
- Yuan Wang (ORCID: https://orcid.org/0000-0002-4645-3916)
- Chengnan Wu
Institutions
- Sun Yat-sen University (CN)
- City University of Hong Kong (HK)
- Guangdong Pharmaceutical University (CN)
- National Research Tomsk State University (RU)
- Tomsk Polytechnic University (RU)
- Nikolaev Institute of Inorganic Chemistry (RU)
Publication Details
- Journal
- Inorganic Chemistry Frontiers
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1039/d5qi00868a
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00