A challenging chest X-ray in the pediatric immunocompetent patient
Abstract Granulomatosis with polyangiitis (GPA) is a necrotizing vasculitis of the small and medium-sized vessels which manifests as a multisystemic disease involving the upper and lower respiratory tract and the kidneys. The typical age at diagnosis is between 45 and 60 years of age, and childhood onset is rare. Here, we discuss a case of pediatric GPA presenting with a cavitary lung lesion, sinusitis, and glomerulonephritis. This case report underlines the importance of considering GPA among the differential diagnoses of cavitary lung lesions in the pediatric age, especially in the immunocompetent patient and when associated with multisystemic disease.
Authors
- Marcello Napolitano (ORCID: https://orcid.org/0000-0003-0288-3858)
- Andrea Pasini (ORCID: https://orcid.org/0000-0001-8479-8379)
- Laura Greco (ORCID: https://orcid.org/0000-0002-3914-8614)
- Donatella Vivacqua
- Michelangelo Baldazzi (ORCID: https://orcid.org/0000-0002-5439-512X)
- Eugenio Rossi
- Francesco Galuppi (ORCID: https://orcid.org/0009-0005-9106-0838)
- Giuseppe Paviglianiti
- Laura Marcolin
- Vittoria Camelli
- Francesca Mariani
- Elena Maria Tarì
- Andrea Zavatta
Institutions
- Ospedale Maggiore Carlo Alberto Pizzardi (IT)
- Azienda USL di Bologna (IT)
- Santobono Children's Hospital (IT)
- Ospedale dei Bambini Vittore Buzzi (IT)
- Azienda di Rilievo Nazionale ed Alta Specializzazione (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Journal of Medical Imaging and Interventional Radiology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1007/s44326-025-00079-6
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00