iPSC-derived MSCs alleviate arthritis in collagen-induced arthritis mice by reducing synovial CD86h iIL1βhi macrophage
iMSCs effectively alleviate inflammation and bone damage in CIA by modulating macrophage phenotypes, demonstrating potential for RA therapy.
Authors
- Linxin Li (ORCID: https://orcid.org/0000-0002-3636-8355)
- Yazhen Su (ORCID: https://orcid.org/0000-0002-9512-5257)
- Zewen Wu (ORCID: https://orcid.org/0000-0001-9124-4577)
- Chong Gao (ORCID: https://orcid.org/0000-0001-7639-0808)
- Xinling Liu (ORCID: https://orcid.org/0000-0003-3106-670X)
- Jingxuan Li (ORCID: https://orcid.org/0000-0002-4212-0559)
- Yang Liu (ORCID: https://orcid.org/0000-0003-1859-6300)
- Liyun Zhang (ORCID: https://orcid.org/0000-0002-0814-4872)
- Mingze Yao (ORCID: https://orcid.org/0009-0008-2385-0434)
- Li Zhao (ORCID: https://orcid.org/0009-0009-8940-8873)
Institutions
- Brigham and Women's Hospital (US)
- Shanxi Medical University (CN)
- Shanxi University (CN)
- Jinzhong University (CN)
- Theranostics (New Zealand) (NZ)
- Institute for Rheumatic Diseases (Japan) (JP)
- Shanxi Academy of Medical Sciences (CN)
Publication Details
- Journal
- Stem Cells Translational Medicine
- Published
- 2025-09-28
- DOI
- https://doi.org/10.1093/stcltm/szaf045
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00