Predicting cervical lymph node metastasis in papillary thyroid carcinoma using capsule disruption length measured by 3D-US
Question Can the LCD measured by 3D-US predict cervical LNM in PTC? Findings LCD ≥ 0.42 cm on 3D-US increase LNM risk by 4.097-fold. The nomogram with LCD, gender, age, and nodule size shows good predictive ability (AUC = 0.795). Clinical relevance LCD is a promising predictor of LNM, an alternative to ultrasound thyroid capsule invasion evaluation. The nomogram enables risk-adapted surgery, reducing unnecessary dissection or missed metastases to improve patient outcomes.
Authors
- Luying Gao (ORCID: https://orcid.org/0000-0001-7318-3897)
- Xingjian Lai
- Ruina Zhao (ORCID: https://orcid.org/0000-0002-1643-2460)
- Xuehua Xi
- Bo Zhang (ORCID: https://orcid.org/0000-0003-3389-5018)
- Ying Wang (ORCID: https://orcid.org/0000-0002-1241-6252)
- Yuxin Jiang (ORCID: https://orcid.org/0000-0002-8388-7262)
- Ruyu Liu (ORCID: https://orcid.org/0000-0001-7561-9439)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- European Radiology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1007/s00330-025-12070-6
- Citations
- 1
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- China-Japan Friendship Hospital