Longitudinal changes in estimated glucose disposal rate and risk of cardiovascular disease among adults with cardiovascular–kidney–metabolic syndrome stages 0–3: a nationwide prospective cohort study
Lower cumulative eGDR and unfavorable eGDR trajectories are significantly associated with increased CVD risk among individuals in CKM stages 0-3. These findings suggest that monitoring eGDR may enhance early CVD risk prediction and guide prevention strategies in this population.
Authors
- Yufei Zeng (ORCID: https://orcid.org/0000-0002-2232-8029)
- Rui Zeng (ORCID: https://orcid.org/0000-0002-8499-6743)
- Jiahui Bian (ORCID: https://orcid.org/0000-0002-0121-4217)
- Mei Shi
- Kun Huang
- Mingxing Lai (ORCID: https://orcid.org/0000-0002-2206-5572)
- Ruohan Wu (ORCID: https://orcid.org/0000-0002-0468-9920)
- Yi Xiao (ORCID: https://orcid.org/0000-0002-5124-8378)
- Wenwu Zhang (ORCID: https://orcid.org/0000-0002-1402-3508)
- Lihuan Chen (ORCID: https://orcid.org/0009-0007-7936-9212)
- Dongmei Ye (ORCID: https://orcid.org/0000-0003-0247-3891)
- Yunfeng Liu (ORCID: https://orcid.org/0000-0003-2826-5804)
- Xiaoming Zhang (ORCID: https://orcid.org/0000-0002-0827-727X)
- Zhigang Wu
- Zhiqi Jiang (ORCID: https://orcid.org/0009-0007-5474-4362)
- Xirong Sun
- Jiang Wang (ORCID: https://orcid.org/0000-0003-2320-7576)
- Yunzhi Yang
- Wan Zhu
- Aizhang Zhu
- Huajing Wu
- Tenghui Fan
- Ke Zhu (ORCID: https://orcid.org/0009-0000-9997-5665)
- Fayi Xie
- Siyi Wang (ORCID: https://orcid.org/0009-0001-2639-2263)
Institutions
- Jinggangshan University (CN)
- Jinan University (CN)
- Soochow University (CN)
- Shenzhen Bao'an District People's Hospital (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1186/s40001-025-03286-9
- Primary Topic
- Diabetes Management and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00