Genome Sequencing to Prevent Hospital-Acquired Infections Caused by Carbapenem-Resistant Acinetobacter baumannii Due to Importation and Intra-facility Transmission in a Regional Hospital Network: Study Protocol for Implementation Research

The study shall generate evidence on genoepidemiology, transmission dynamics of HAIs due to CRAb in Odisha, India, and the associated risk factors. The lessons from context-specific implementation strategies (covering infection surveillance, prevention strategies, and antibiotic stewardship domains) to tackle CRAb-associated HAIs outbreaks and the feasibility, acceptability, and sustainability shall inform the policy and practices. The geographic signatures of horizontal CRAb-associated HAIs will generate a new knowledge base to design future intervention measures.

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Publication Details

Journal
Cureus
Published
2025-10-17
DOI
https://doi.org/10.7759/cureus.94812
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
0.00

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article

Genome Sequencing to Prevent Hospital-Acquired Infections Caused by Carbapenem-Resistant Acinetobacter baumannii Due to Importation and Intra-facility Transmission in a Regional Hospital Network: Study Protocol for Implementation Research

Priya Ranjan Lenka, Basanti Kumari Pathi, Balamurugan Ramadass, Kumudini Panigrahi et al.
Cureus
Antibiotic Resistance in Bacteria
article

Genome Sequencing to Prevent Hospital-Acquired Infections Caused by Carbapenem-Resistant Acinetobacter baumannii Due to Importation and Intra-facility Transmission in a Regional Hospital Network: Study Protocol for Implementation Research

Priya Ranjan Lenka, Basanti Kumari Pathi, Balamurugan Ramadass, Kumudini Panigrahi, Shikha Dixit, Rajashree Panigrahy, Ashoka Mahapatra, Manoja Kumar Das, Jyoti Prakash Sahoo, Indrani Mohanty, Sanghamitra Padhi
article en

Abstract

The study shall generate evidence on genoepidemiology, transmission dynamics of HAIs due to CRAb in Odisha, India, and the associated risk factors. The lessons from context-specific implementation strategies (covering infection surveillance, prevention strategies, and antibiotic stewardship domains) to tackle CRAb-associated HAIs outbreaks and the feasibility, acceptability, and sustainability shall inform the policy and practices. The geographic signatures of horizontal CRAb-associated HAIs will generate a new knowledge base to design future intervention measures.

CureusVol. 17(10)
Siksha O Anusandhan University (IN), Maharaja Krishna Chandra Gajapati Medical College and Hospital (IN), Lahey Medical Center (US), Index Medical College, Hospital & Research Centre (IN), All India Institute of Medical Sciences Bhubaneswar (IN), Institute of Medical Sciences and Sum Hospital (IN), INCLEN Trust International (IN)
Indian Council of Medical Research
Openalex Percentile: Top 76%
Antibiotic Resistance in Bacteria
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