Comparative Performance Analysis of Corneal Characteristics During Extended Hypothermic Storage in XTRA4 and Optisol-GS

XTRA4 preserves the corneal endothelium similarly to Optisol-GS for up to 14 days while maintaining consistently thinner corneas for up to 28 days. This antiswelling property may improve eye bank logistics and support future laboratory and clinical studies toward extending hypothermic storage beyond the current 14-day limit.

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Publication Details

Journal
Cornea
Published
2025-10-02
DOI
https://doi.org/10.1097/ico.0000000000004003
Primary Topic
Corneal surgery and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparative Performance Analysis of Corneal Characteristics During Extended Hypothermic Storage in XTRA4 and Optisol-GS

Eugenio Ragazzi, Megan M. W. Straiko, Khoa Tran, Mark S. Ellison et al.
Cornea
Corneal surgery and disorders
article

Comparative Performance Analysis of Corneal Characteristics During Extended Hypothermic Storage in XTRA4 and Optisol-GS

Eugenio Ragazzi, Megan M. W. Straiko, Khoa Tran, Mark S. Ellison, Declan Z. Chamberlain
article en

Abstract

XTRA4 preserves the corneal endothelium similarly to Optisol-GS for up to 14 days while maintaining consistently thinner corneas for up to 28 days. This antiswelling property may improve eye bank logistics and support future laboratory and clinical studies toward extending hypothermic storage beyond the current 14-day limit.

CorneaVol. 45(3)
University of Padua (IT)
Openalex Percentile: Top 57%
Corneal surgery and disorders
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