In vitro comparison of biological properties of CoCr, Ti-6Al-4V, and PEEK for removable partial denture

Machined titanium (Ti) and PEEK exhibited favorable in vitro biocompatibility, with high cell viability, enhanced cellular adhesion, and no significant cytotoxicity under our experimental conditions. These findings suggest that both materials may represent promising alternatives to CoCr alloys for the fabrication of removable partial dentures, although their clinical application requires further validation of their mechanical, physical, and long-term properties.

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Publication Details

Journal
Dental Materials
Published
2025-10-17
DOI
https://doi.org/10.1016/j.dental.2025.10.001
Primary Topic
Dental materials and restorations
Type
article
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article

In vitro comparison of biological properties of CoCr, Ti-6Al-4V, and PEEK for removable partial denture

Brigitte Grosgogeat, Christophe Sireix, Christophe Jeannin, Nina Attik et al.
Dental Materials
Dental materials and restorations
article

In vitro comparison of biological properties of CoCr, Ti-6Al-4V, and PEEK for removable partial denture

Brigitte Grosgogeat, Christophe Sireix, Christophe Jeannin, Nina Attik, Angéline Poulon‐Quintin, Karine Bertotti, Julia Mwenge-Wambel
article en

Abstract

Machined titanium (Ti) and PEEK exhibited favorable in vitro biocompatibility, with high cell viability, enhanced cellular adhesion, and no significant cytotoxicity under our experimental conditions. These findings suggest that both materials may represent promising alternatives to CoCr alloys for the fabrication of removable partial dentures, although their clinical application requires further validation of their mechanical, physical, and long-term properties.

Dental MaterialsVol. 42(2)
Université Claude Bernard Lyon 1 (FR), Centre National de la Recherche Scientifique (FR), Université de Bordeaux (FR), Xerox (France) (FR), Laboratoire des Multimatériaux et Interfaces (FR), Institut Polytechnique de Bordeaux (FR)
Openalex Percentile: Top 69%
Dental materials and restorations
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In vitro comparison of biological properties of CoCr, Ti-6Al-4V, and PEEK for removable partial denture — Brigitte Grosgogeat, Christophe Sireix, et al. · Dental Materials (2025) | TGRS Research Map | TGRS