Phase II study of salvage HDR brachytherapy combined with external beam radiotherapy for isolated prostate bed relapse after radical prostatectomy: preliminary clinical results

Combined salvage HDR brachytherapy followed by EBRT for PSMA-detected IPBR is feasible, achieves excellent early biochemical control, and preserves quality of life with favorable toxicity. The trial was closed without completing the target size due to slow accrual although these results warrant confirmation in larger multicenter trials.

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Publication Details

Journal
Radiotherapy and Oncology
Published
2025-10-17
DOI
https://doi.org/10.1016/j.radonc.2025.111215
Citations
1
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.52
Controls
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article

Phase II study of salvage HDR brachytherapy combined with external beam radiotherapy for isolated prostate bed relapse after radical prostatectomy: preliminary clinical results

Adriana Ayestarán, Marcos Torres, Rafael Martínez‐Monge, Javier Ancizu‐Marckert et al.
1 citations
Radiotherapy and Oncology
Prostate Cancer Diagnosis and Treatment
1.52
article

Phase II study of salvage HDR brachytherapy combined with external beam radiotherapy for isolated prostate bed relapse after radical prostatectomy: preliminary clinical results

Adriana Ayestarán, Marcos Torres, Rafael Martínez‐Monge, Javier Ancizu‐Marckert, Alberto Benito, M. Teresa Fontanilla Echeveste, Macarena Rodríguez‐Fraile, Benigno Barbés, Luis Labairu Huerta, Sara Fadrique, Luis Fuertes Vallés, Marian Aristu Mendioroz
article en
1 citations

Abstract

Combined salvage HDR brachytherapy followed by EBRT for PSMA-detected IPBR is feasible, achieves excellent early biochemical control, and preserves quality of life with favorable toxicity. The trial was closed without completing the target size due to slow accrual although these results warrant confirmation in larger multicenter trials.

Radiotherapy and OncologyVol. 213
Clinica Universidad de Navarra (ES)
Openalex Percentile: Top 13%
Prostate Cancer Diagnosis and Treatment
1.52
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Phase II study of salvage HDR brachytherapy combined with external beam radiotherapy for isolated prostate bed relapse after radical prostatectomy: preliminary clinical results — Adriana Ayestarán, Marcos Torres, et al. · Radiotherapy and Oncology (2025) | TGRS Research Map | TGRS