Weak Coordination-Assisted Cobalt(III)-Catalyzed Regioselective Alkenylation of Indolines with Allenes

Abstract A cobalt(III)-catalyzed regioselective coupling of indolines with allenes is reported to access C7-alkenyl indolines in good to high yields. The method features weakly coordinating-group assistance, broad functional-group tolerance, including pharmacophores, scalability, and a reversible C–H activation step.

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Publication Details

Journal
Synlett
Published
2025-10-17
DOI
https://doi.org/10.1055/a-2726-4670
Primary Topic
Catalytic C–H Functionalization Methods
Type
article
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0.00
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article

Weak Coordination-Assisted Cobalt(III)-Catalyzed Regioselective Alkenylation of Indolines with Allenes

Mainak Koner, Mahiuddin Baidya, Shabbir Ahmed Khan
Synlett
Catalytic C–H Functionalization Methods
article

Weak Coordination-Assisted Cobalt(III)-Catalyzed Regioselective Alkenylation of Indolines with Allenes

Mainak Koner, Mahiuddin Baidya, Shabbir Ahmed Khan
article en

Abstract

Abstract A cobalt(III)-catalyzed regioselective coupling of indolines with allenes is reported to access C7-alkenyl indolines in good to high yields. The method features weakly coordinating-group assistance, broad functional-group tolerance, including pharmacophores, scalability, and a reversible C–H activation step.

Synlett
Indian Institute of Technology Madras (IN)
Openalex Percentile: Top 78%
Catalytic C–H Functionalization Methods
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Weak Coordination-Assisted Cobalt(III)-Catalyzed Regioselective Alkenylation of Indolines with Allenes — Mainak Koner, Mahiuddin Baidya, et al. · Synlett (2025) | TGRS Research Map | TGRS