International Session 14　　Larynx

The efficacy of intracordal trafermin injection for diseases such as age-related vocal fold atrophy and paralysis has been reported from various previous studies.However, intracordal trafermin injection is currently not indicated in Japan.We aimed to expand the indication for a new route of trafermin administration into the vocal folds, and proved its safety and efficacy.As a result, a protocol and SOP(Standard Operating Procedures)were developed, and a specific clinical study of intracordal trafermin injection is planned.In this report, we describe the history and future prospects of this study.