Regression from prediabetes to normoglycaemia and the role of cardiometabolic risk factors on the subsequent risk of developing type 2 diabetes
Our results suggest that prioritising normoglycaemia restoration during the prediabetes stage in clinical guidelines may contribute to reducing the risk of type 2 diabetes, particularly when accompanied by favourable cardiometabolic health profiles.
Authors
- Hiroshi Yatsuya (ORCID: https://orcid.org/0000-0002-6220-9251)
- Alain G. Bertoni (ORCID: https://orcid.org/0000-0002-7503-6273)
- Rachel Huxley (ORCID: https://orcid.org/0000-0002-2705-6616)
- Morgana Mongraw‐Chaffin (ORCID: https://orcid.org/0000-0001-6541-7198)
- Najmeh Davoodian (ORCID: https://orcid.org/0000-0001-6410-6400)
- Jonathan E. Shaw (ORCID: https://orcid.org/0000-0002-6187-2203)
- Mohammadreza Mohebbi (ORCID: https://orcid.org/0000-0001-9713-7211)
- Farzad Hadaegh (ORCID: https://orcid.org/0000-0002-0352-8666)
- Crystal Lee (ORCID: https://orcid.org/0000-0001-6613-5491)
- Robert Adams (ORCID: https://orcid.org/0000-0002-7572-0796)
- Mojtaba Lotfaliany (ORCID: https://orcid.org/0000-0001-6594-9004)
- Gita Devi Mishra (ORCID: https://orcid.org/0000-0001-9610-5904)
- Dianna J. Magliano (ORCID: https://orcid.org/0000-0002-9507-6096)
- Stephen Colagiuri (ORCID: https://orcid.org/0000-0002-2398-4781)
- Edward W. Gregg (ORCID: https://orcid.org/0000-0003-2381-6822)
- Masaru Sakurai (ORCID: https://orcid.org/0000-0002-4929-3225)
- Julie Anne Pasco (ORCID: https://orcid.org/0000-0002-8968-4714)
- Tiffany K. Gill (ORCID: https://orcid.org/0000-0002-2822-2436)
- Davood Khalili (ORCID: https://orcid.org/0000-0003-4956-1039)
- Fereidoun Azizi (ORCID: https://orcid.org/0000-0002-7335-3873)
Institutions
- The University of Sydney (AU)
- Barwon Health (AU)
- Baker Heart and Diabetes Institute (AU)
- Deakin University (AU)
- The University of Queensland (AU)
- Kanazawa Medical University (JP)
- Curtin University (AU)
- UNSW Sydney (AU)
- Women's and Children's Health Network (AU)
- Research Institute for Endocrine Sciences (IR)
- The George Institute for Global Health (AU)
- Western Health (AU)
- Adelaide Institute for Sleep Health (AU)
- Wake Forest University (US)
- Imperial College London (GB)
- Monash University (AU)
- The University of Adelaide (AU)
- Shahid Beheshti University of Medical Sciences (IR)
- Nagoya University (JP)
- MedStar Health (US)
Publication Details
- Journal
- Diabetologia
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1007/s00125-025-06555-8
- Citations
- 4
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 5.18
Funders
- U.S. Department of Health and Human Services
- Deakin University
- Barwon Health Foundation
- National Institutes of Health
- National Health and Medical Research Council
- National Heart, Lung, and Blood Institute