Pilot Feasibility and Preliminary Cost Implications of a Day-Case Head and Neck Surgery Pathway Incorporating ARTISS Fibrin Sealant

A standardized day-case pathway that incorporates ARTISS was feasible in this retrospective pilot, with a preliminary favorable safety profile and cost consequences in an NHS setting. As a single-center, non-comparative study, findings are preliminary and cannot isolate the independent effect of ARTISS. Future studies should include multicenter comparative evaluation (ARTISS versus no ARTISS within the same pathway) and formal economic analysis.