Therapeutic efficacy of cannabidiol on pruritus and pain in children with recessive dystrophic epidermolysis bullosa: a pilot study

This prospective pilot interventional study aimed at studying the efficacy of cannabidiol on pruritus and pain on paediatric patients with recessive dystrophic epidermolysis bullosa. A decrease in average chronic pruritus and pain, pruritus and pain during dressing changes in addition to a significant improvement of quality-of-life scores and sleep were observed. No severe side effects were reported.

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Publication Details

Journal
British Journal of Dermatology
Published
2025-10-17
DOI
https://doi.org/10.1093/bjd/ljaf400
Primary Topic
Transgenic Plants and Applications
Type
article
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article

Therapeutic efficacy of cannabidiol on pruritus and pain in children with recessive dystrophic epidermolysis bullosa: a pilot study

N. Bellon, Céline Greco, Pauline Bataille, Lara Mayrand et al.
British Journal of Dermatology
Transgenic Plants and Applications
article

Therapeutic efficacy of cannabidiol on pruritus and pain in children with recessive dystrophic epidermolysis bullosa: a pilot study

N. Bellon, Céline Greco, Pauline Bataille, Lara Mayrand, Fabienne Marquant, J. Bonigen, Christine Bodemer, S. Chaumon, N. Schinkel, Caroline Elie, Imène Fettouche
article en

Abstract

This prospective pilot interventional study aimed at studying the efficacy of cannabidiol on pruritus and pain on paediatric patients with recessive dystrophic epidermolysis bullosa. A decrease in average chronic pruritus and pain, pruritus and pain during dressing changes in addition to a significant improvement of quality-of-life scores and sleep were observed. No severe side effects were reported.

British Journal of DermatologyVol. 194(2)
Hôpital Necker-Enfants Malades (FR), Inserm (FR), Université Paris Cité (FR), Institut Necker Enfants Malades (FR), Assistance Publique – Hôpitaux de Paris (FR), Institut des Maladies Génétiques Imagine (FR)
Openalex Percentile: Top 68%
Transgenic Plants and Applications
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