Advancing Cancer Biology: Highlights from the 2025 FASEB SRC on Cellular Plasticity in Cancer
The inaugural FASEB Science Research Conference (SRC) on Cellular Plasticity in Cancer was held in May 2025 in Hong Kong SAR, China. This event brought together leading experts to discuss cutting-edge research centered on cancer cell plasticity. The conference featured comprehensive presentations covering a broad spectrum of topics, including oncofetal reprogramming in tumor development and progression, mechanisms regulating cancer cell plasticity, metabolic reprogramming and its role in tumor progression, cancer cell plasticity during metastasis, cancer stem cell programs within the tumor microenvironment, tumor plasticity and immune evasion, as well as innovative therapeutic strategies aimed at targeting stem cell-like states, modulating cancer cell states, and effectively controlling disease progression. It is anticipated that the insights gained from this meeting will catalyze further advancements in cancer biology and therapy.
Authors
- Sheila Kumari Singh (ORCID: https://orcid.org/0000-0003-1272-5300)
- Justin Durla Lathia (ORCID: https://orcid.org/0000-0003-3168-7290)
- Terence K. Lee (ORCID: https://orcid.org/0000-0003-0682-322X)
- Tyler E. Miller (ORCID: https://orcid.org/0000-0002-1269-1895)
- Karuna Ganesh (ORCID: https://orcid.org/0000-0002-4948-1082)
- Vivian Li (ORCID: https://orcid.org/0000-0003-2041-0085)
- Loic P. Deleyrolle
- Anna Golebiewska (ORCID: https://orcid.org/0000-0002-4160-2521)
- Stephanie Ma (ORCID: https://orcid.org/0000-0002-2029-7943)
- Axel Behrens (ORCID: https://orcid.org/0000-0002-1557-1143)
- Walid T. Khaled (ORCID: https://orcid.org/0000-0001-9068-5776)
- Hans Clevers (ORCID: https://orcid.org/0000-0002-3077-5582)
- Sendurai A. Mani (ORCID: https://orcid.org/0000-0002-5918-4276)
- Wai Leong Tam (ORCID: https://orcid.org/0000-0003-2365-5264)
- Dean G. Tang (ORCID: https://orcid.org/0000-0001-5029-1174)
- Shaheen S. Sikandar
- Ankur Sharma (ORCID: https://orcid.org/0000-0001-9339-6988)
- Huiping Liu (ORCID: https://orcid.org/0000-0003-4822-7995)
Institutions
- Agency for Science, Technology and Research (SG)
- Roche (Switzerland) (CH)
- Roswell Park Comprehensive Cancer Center (US)
- Cleveland Clinic (US)
- Memorial Sloan Kettering Cancer Center (US)
- Garvan Institute of Medical Research (AU)
- Hong Kong Polytechnic University (HK)
- Institute of Cancer Research (GB)
- National University of Singapore (SG)
- University of California, Santa Cruz (US)
- Wellcome/MRC Cambridge Stem Cell Institute (GB)
- University of Cambridge (GB)
- Brown University (US)
- Juravinski Cancer Centre (CA)
- Breast Cancer Now (GB)
- The Francis Crick Institute (GB)
- McMaster University Medical Centre (CA)
- Jacksonville College (US)
- Cleveland Clinic Lerner College of Medicine (US)
- Luxembourg Institute of Health (LU)
- National University Cancer Institute, Singapore (SG)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- Case Comprehensive Cancer Center
- Imperial College London (GB)
- Case Western Reserve University (US)
- Genome Institute of Singapore (SG)
- University of Hong Kong (HK)
- McMaster University (CA)
Publication Details
- Journal
- Cancer Heterogeneity and Plasticity
- Published
- 2025-10-17
- DOI
- https://doi.org/10.47248/chp2502040018
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Croucher Foundation